Ashley Shields has had a rough year following the death of her mother, the disintegration of her marriage, and getting passed over for a promotion at work. So when her sister Jasmine brings her to a women's group, The Sisterhood, she is intrigued, and hopes to feel empowered enough to change her life. Led by the enigmatic and charismatic Desiree, The Sisterhood delivers to Ashley everything it promises. She gets a raise at her job, her divorce is resolved in her favor, and she finally feels fulfilled and happy. But she soon discovers that the benefits of The Sisterhood come at a steep--and sometimes illegal--price. As she learns more about The Sisterhood and is forced to participate in its questionable activities, she realizes that she is in over her head and must get out--even if it's at the expense of her relationship with Jasmine--or at the cost of her life.

Amber Vickers is ecstatic that she will finally be making the walk down the aisle with her prince charming Luke. After multiple failed relationships, she was beginning to think that something was wrong; but her soon-to-be mother-in-law and best friend, Jill, believes that Amber is the picture-perfect daughter she never had. Everything is coming up roses until Sharon Vickers, Amber's mother, arrives for a visit. Gaudy, straight-laced and opinionated, Sharon is the complete opposite of Jill. What was supposed to be a benign first meeting of the in-law's quickly turns into a competition, as Sharon and Jill have widely differing views on life, love and marriage. As the weekend visit is coming to an end, Sharon takes matters into her own hands, rendering Jill incapable of escaping her house, and proving to her once and for all that no one comes between Sharon and her daughter.

Posy Pinkerton (Christa B. Allen) mantém um relacionamento morno com Tom, um médico com quem está prestes a se casar. Quando a jovem conhece o charmoso Jack, um homem mais velho que diz ser casado, um desejo adormecido desperta em Posy, fazendo com que ela se envolva em um perigoso esquema.

Elizabeth Marshall está concorrendo ao governo do estado da Pensilvânia quando sua filha que foi roubada da maternidade reaparece. Uma sensação na mídia, a situação é muito favorável a campanha. Porém, as coisas se complicam quando Terri, a outra filha de Elizabeth, se sente ameaçada pela chegada da nova irmã.